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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFHD2 All Species: 18.79
Human Site: T84 Identified Species: 34.44
UniProt: Q96C19 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96C19 NP_077305.2 240 26697 T84 R R V F N P Y T E F K E F S R
Chimpanzee Pan troglodytes XP_001156210 410 44344 T254 R R V F N P Y T E F K E F S R
Rhesus Macaque Macaca mulatta Q5TM25 147 16701 E26 Q Q E E R L D E I N K Q F L D
Dog Lupus familis XP_848956 248 27200 L89 F G V C S P G L E S Q L Q A G
Cat Felis silvestris
Mouse Mus musculus Q9D8Y0 240 26773 T84 R R V F N P Y T E F K E F S R
Rat Rattus norvegicus Q4FZY0 239 26741 T83 R R V F N P Y T E F K E F S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518105 170 19250 K48 F I D L M E L K L M M E K L E
Chicken Gallus gallus P09860 161 18412 E40 D G C I S T K E L G K V M R M
Frog Xenopus laevis NP_001089944 202 23367 G71 Q F D A G H D G F I D L M E L
Zebra Danio Brachydanio rerio NP_001038676 233 26492 T77 M K V F N P Y T E F K E F S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJ26 217 25068 I71 P E F S R N Q I K D Y Q K T F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001176294 193 22506 Y70 I D M M E L K Y M M E K L E A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LQN4 166 18399 G45 G S L L R A L G V K P S P D Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58 25.8 62 N.A. 94.1 93.3 N.A. 60 20 70.4 75 N.A. 45.8 N.A. N.A. 53.3
Protein Similarity: 100 58.2 37.9 68.9 N.A. 97 96.6 N.A. 64.1 38.7 76.6 83.7 N.A. 60.8 N.A. N.A. 63.7
P-Site Identity: 100 100 13.3 20 N.A. 100 100 N.A. 6.6 6.6 0 86.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 33.3 40 N.A. 100 100 N.A. 6.6 13.3 6.6 93.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 16 0 0 0 16 0 0 8 8 0 0 8 8 % D
% Glu: 0 8 8 8 8 8 0 16 47 0 8 47 0 16 8 % E
% Phe: 16 8 8 39 0 0 0 0 8 39 0 0 47 0 8 % F
% Gly: 8 16 0 0 8 0 8 16 0 8 0 0 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 8 0 0 0 8 8 8 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 16 8 8 8 54 8 16 0 0 % K
% Leu: 0 0 8 16 0 16 16 8 16 0 0 16 8 16 8 % L
% Met: 8 0 8 8 8 0 0 0 8 16 8 0 16 0 8 % M
% Asn: 0 0 0 0 39 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 47 0 0 0 0 8 0 8 0 0 % P
% Gln: 16 8 0 0 0 0 8 0 0 0 8 16 8 0 8 % Q
% Arg: 31 31 0 0 24 0 0 0 0 0 0 0 0 8 39 % R
% Ser: 0 8 0 8 16 0 0 0 0 8 0 8 0 39 0 % S
% Thr: 0 0 0 0 0 8 0 39 0 0 0 0 0 8 0 % T
% Val: 0 0 47 0 0 0 0 0 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 39 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _